I'm a longtime 40k fan and Rogue Trader is one of the few games that I feel like really nail the setting spot on. And I also enjoyed Owlcat's Pathfinder games, they've got a strong pedigree behind them. If you're a fan of CRPGs and Warhammer 40k you should definitely pick it up, it's great. If you're not a 40k fan, the game is still good, but you've got some homework to do if you want to understand the setting and understand the decisions you're making - the Pathfinders might be a better fit for you.